A prospective study to determine the safety and feasibility of opioid-free discharge after percutaneous nephrolithotomy

This feasibility study demonstrates that patients undergoing PCNL via a standardized nonopioid pathway can be safely discharged without opioid prescriptions without impact on outpatient resources. Four participants in the pre-intervention group were discharged without opioids based on provider discretion, suggesting that the standard of care to include an opioid prescription may be changing.