Analysis of the burden of disease for male infertility globally and in China from 1990 to 2021

This study underscores the increasing global burden of male infertility, accompanied by pronounced disparities across regions and socioeconomic groups. While the burden in China shows signs of decline, low and low-middle SDI regions continue to face rising prevalence and DALYs. Official attention, along with a comprehensive approach to managing environmental factors, lifestyle changes, and sexually transmitted diseases (STDs), is essential to address these disparities and mitigate the growing global burden of male infertility.