Reconsidering Social-Behavioral Phenotypes in Wolf–Hirschhorn Syndrome: Presentation of Two Cases Diagnosed with Autism Spectrum Disorder

This case series demonstrates the need to comprehensively assess rather than merely screen ASD symptomatology in children with WHS, taking into account their degree of cognitive impairment. Increased awareness of this co-occurring diagnosis can help promote early identification by diagnosticians and monitoring by other medical providers caring for children with WHS, thereby enabling families to connect to appropriate intervention services.