Beyond the Liver: Exploring the Uncommon Link between Cecal Perforation and Amebiasis

A BSTRACT This case series explores the rare association between caecal perforation and amebiasis, a parasitic infection typically linked to liver abscesses. Six patients with both conditions were analyzed, revealing common presentations of high fever, abdominal pain, and peritonitis. The study highlights the diagnostic challenges, as X-rays may not always indicate bowel perforation. Management primarily involved surgical intervention, including cecal resection and ileostomy. Despite treatment, mortality remains high due to post-operative sepsis. The findings underscore the importance of early surgical intervention and awareness of this uncommon, potentially fatal, manifestation of amebiasis, particularly in immunocompromised individuals.