Prebiotics Rescue Gut Microbiome Dysregulation and Enhance Cognitive and Gastrointestinal Function in a Mouse Model of Schizophrenia
These preclinical findings indicate that prebiotics, such as the combination of FOS and GOS used in the present study, may have therapeutic potential in schizophrenia as an add-on intervention with an exceptional safety profile.
Authors
- Thibault Renoir (ORCID: https://orcid.org/0000-0002-9262-3971)
- Geraldine Kong (ORCID: https://orcid.org/0000-0001-9277-8650)
- Bethany A. Masson
- Vinod K. Narayana (ORCID: https://orcid.org/0000-0003-3980-7496)
- Carolina Gubert (ORCID: https://orcid.org/0000-0002-8078-1390)
- Anthony J. Hannan (ORCID: https://orcid.org/0000-0001-7532-8922)
- N van de Garde
- Sasha Connell
- Sheida Shadani
Institutions
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- Peter Doherty Institute (AU)
- Institute of Infection and Immunity (CA)
- Melbourne Genomics Health Alliance (AU)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1093/schbul/sbaf056
- Citations
- 3
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Equity Trustees