Pathogenesis and Treatment of Hepatocellular Carcinoma Associated with Nonalcoholic Steatohepatitis

肝细胞癌(HCC)目前仍是全球最常见的恶性肿瘤之一，具有较高的发病率和死亡率。近些年的趋势表明，非酒精性脂肪性肝病(NAFLD)的全球发病率在不断增加，成为HCC新病例的主要贡献者之一。本文对非酒精性脂肪性肝炎相关肝细胞癌的流行病学、发病机制、临床管理进行综述，以期为进一步研究和治疗非酒精性脂肪性肝炎相关肝细胞癌提供新的思路和参考。Hepatocellular carcinoma (HCC) remains one of the most common malignant tumors globally, with high incidence and mortality rates. Trends in recent years indicate that the global prevalence of non-alcoholic fatty liver disease (NAFLD) has been increasing, making it one of the primary contributors to new HCC cases. This article reviews the epidemiology, pathogenesis, and clinical management of hepatocellular carcinoma associated with nonalcoholic steatohepatitis (NASH), aiming to provide new insights and references for further research and treatment of this condition.