Assessment of Rhinitis Control Assessment Test Score after Vitamin D Supplementation along with Standard Regimen in Patients of Allergic Rhinitis – A Prospective Randomized Control Trial

Abstract Background: Allergic rhinitis (AR) affects 10%–20% of the global population, significantly impacting daily activities and quality of life. It has varied clinical presentations including sneezing, nasal discharge, and watering and itching in the eyes. The role of Vitamin D supplementation has been considered nowadays as one of the important aspects in the management of AR, and the same was assessed in the present study. Aim: Assessment and comparison of Rhinitis Control Assessment Test (RCAT) and TNSS score in patients of AR in both the groups. Methods: This 18-month randomized controlled trial was conducted in 160 patients of AR divided into two groups (Group A = standard regimen and Group B = Vitamin D supplementation along with standard regimen). The study was carried out to assess the RCAT and TNSS scores post-Vitamin D supplementation along with standard regimen. The collected data were analyzed using SPSS software. Results: The pre- and posttreatment TNSS were calculated for both the groups (pretreatment Group A = 10.06 ± 1.56 and Group B = 11.59 ± 1.29; posttreatment Group A = 5.01 ± 0.01, Group B = 2.59 ± 0.49). The posttreatment RCAT scores were significantly higher in Group B (28.60 ± 0.98) as compared to Group A (20.96 ± 1.40). Therefore, Group B showed statistically significant improvement in both RCAT and TNSS scores compared to Group A implying a positive effect of Vitamin D supplementation. Conclusion: Vitamin D supplementation along with standard regimen showed significant improvement in the symptomatology and quality of life in AR patients due to its immunomodulation property as assessed by TNSS and RCAT score.