Global T-cell functionality evaluated by whole blood interferon-gamma release assay as a valuable indicator for immune reconstitution monitoring in pediatric allo-HSCT

This study demonstrated the potential application of the WB-IGRA approach in evaluating and monitoring T-cell IR in pediatric allo-HSCT recipients. Combining the assessment of T-cell immune functionality with cellular phenotypes could enhance the understanding of T-cell IR in HSCT children of different ages.

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Publication Details

Journal
Translational Pediatrics
Published
2025-05-01
DOI
https://doi.org/10.21037/tp-2025-80
Citations
1
Primary Topic
Heparin-Induced Thrombocytopenia and Thrombosis
Type
article
Field-Weighted Citation Impact
2.01
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article

Global T-cell functionality evaluated by whole blood interferon-gamma release assay as a valuable indicator for immune reconstitution monitoring in pediatric allo-HSCT

Aurore Fleurie, Franck Berthier, Xia Qin, Jing Chen et al.
1 citations
Translational Pediatrics
Heparin-Induced Thrombocytopenia and Thrombosis
2.01
article

Global T-cell functionality evaluated by whole blood interferon-gamma release assay as a valuable indicator for immune reconstitution monitoring in pediatric allo-HSCT

Aurore Fleurie, Franck Berthier, Xia Qin, Jing Chen, Min Wang, Qing Cao, Yan Miao, Chengjuan Luo, Changying Luo, Xiaohang Huang, Ji Liang, Liang Ma
article en
1 citations

Abstract

This study demonstrated the potential application of the WB-IGRA approach in evaluating and monitoring T-cell IR in pediatric allo-HSCT recipients. Combining the assessment of T-cell immune functionality with cellular phenotypes could enhance the understanding of T-cell IR in HSCT children of different ages.

Translational PediatricsVol. 14(5)
Shanghai Jiao Tong University (CN), Shanghai Children's Medical Center (CN)
Zero hunger
Openalex Percentile: Top 15%
Heparin-Induced Thrombocytopenia and Thrombosis
2.01
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Global T-cell functionality evaluated by whole blood interferon-gamma release assay as a valuable indicator for immune reconstitution monitoring in pediatric allo-HSCT — Aurore Fleurie, Franck Berthier, et al. · Translational Pediatrics (2025) | TGRS Research Map | TGRS