CORRELATION OF GLUCOSE AND LIPID STATUS IN PATIENTS WITH GESTATIONAL DIABETES MELLITUS

Institute of Medical and Experimental Biochemistry, Faculty of Medicine, "Ss Cyril and Methodius" University, Skopje, Republic of North Macedonia. Gestational diabetes mellitus, characterized by glucose intolerance during pregnancy, poses heightened risks to both the mother and fetus. It emerges due to increased insulin resistance during pregnancy. Adipose tissue plays a vital role in regulating various biological processes through the secretion of adipokines, which influence both pregnancy and the development of gestational diabetes. Hyperlipidemia, a well-known contributor to atherosclerosis, directly impacts the onset of cardiovascular diseases. Pregnancy leads to an increase in serum levels of total cholesterol and triglycerides, driven by increased levels of hormones such as estrogens, progesterone and lactogen.