Global Collaborations in SREBP Research: Scientific Productivity and Impact

Aim: This study provides a comprehensive bibliometric analysis of SREBP research, assessing its scientific impact and evolution over time. Background: Sterol regulatory element-binding proteins (SREBPs) are transcription factors regulating lipid synthesis and uptake. They play vital roles in lipogenesis, endoplasmic reticulum stress, inflammation, autophagy, and apoptosis. Methods: We analyzed original research articles published from 1997 to 2023 using the Web of Science Core Collection database. Data analysis was performed using VOSviewer, Bibliometrix, Biblioshiny, and Microsoft Excel, examining publication outputs, countries, institutions, journals, authors, keywords, and citations. Results: A total of 3,863 articles were identified, authored by 13,910 researchers. The most productive countries were China, the USA, and South Korea, with the USA leading in total citations. Seoul National University and Nanjing Agricultural University were identified as key institutions. The analysis revealed significant global collaborations and emphasized SREBP’s impact on metabolic diseases and cancer biology. Conclusion: This bibliometric analysis offers valuable insights into SREBP research, identifying leading contributors, trends, and future research directions. It serves as a guide for researchers in selecting appropriate journals, collaborators, and focus areas.