A multi-channel wearable sensing patch based on gate-all-around field-effect transistors
Field-effect transistors (FETs), known for their rapid response and signal amplification capabilities, have attracted significant research interest for the detection of biomarkers. However, the development of multi-channel sensors using FETs and their wearable applications are impeded by the rigid substrates and large areas. Here, we reported a wearable EGFET sensor array patch that integrates gate-all-around field-effect transistors (GAA FETs) and flexible printed circuit board (FPCB) patches to overcome these challenges. The patch takes advantage of the excellent electrical properties and small size of GAA FETs, allowing for multi-biomarker detection. Additionally, it integrates large-scale, low-cost FPCB-based electrodes to enhance the flexibility of the patch. Comprehensive characterization experiments have demonstrated the performance of the patch to detect multiple biomarkers, including glucose, lactate, Na<sup>+</sup>, K<sup>+</sup>, and Ca<sup>2+</sup>. This innovative patch is promising to facilitate the development of FET-based multi-channel wearable sensors, and has the potential to help realize more comprehensive health monitoring.
Authors
- Qiang Liu (ORCID: https://orcid.org/0000-0003-3424-4698)
- Hongju Mao (ORCID: https://orcid.org/0000-0003-1613-1032)
- Zhenhua Wu (ORCID: https://orcid.org/0000-0003-4552-883X)
- Wenjie Yu (ORCID: https://orcid.org/0009-0006-1884-3315)
- Yuxin Liu (ORCID: https://orcid.org/0000-0002-2080-487X)
- Shuang Li (ORCID: https://orcid.org/0000-0002-3483-5087)
- Guanhua Zhang (ORCID: https://orcid.org/0000-0002-2751-5202)
- Bo Lin (ORCID: https://orcid.org/0000-0001-5570-3131)
- Zhe Xing (ORCID: https://orcid.org/0009-0002-7797-405X)
Institutions
- Tianjin University (CN)
- Chinese Academy of Sciences (CN)
- Fudan University (CN)
- State Key Laboratory of Transducer Technology (CN)
- Pudong Medical Center (CN)
- Shanghai Institute of Microsystem and Information Technology (CN)
- University of Chinese Academy of Sciences (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Lab on a Chip
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5lc00162e
- Citations
- 1
- Primary Topic
- Advanced Sensor and Energy Harvesting Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Shanghai Engineering Technology Research Center
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Guangzhou Municipal Science and Technology Project
- National Key Research and Development Program of China