Genomewide association analysis on green tea chemoprevention of colorectal adenoma: the importance of SLCO1A2 variants
Individuals with genetic variants in the transporter SLCO1A2 may be protected against colon adenoma irrespective of the green tea intake. In nonvariant carriers of <i>SLCO1A2</i>, green tea was associated with a clear benefit in outcome (18% risk reduction).
Authors
- Michael Steffens (ORCID: https://orcid.org/0000-0002-6445-8593)
- Friederike Rohlmann
- Rainer Muche
- Catharina Scholl (ORCID: https://orcid.org/0000-0002-1463-5619)
- Thomas J. Ettrich (ORCID: https://orcid.org/0000-0002-7654-2442)
- Julia Stingl (ORCID: https://orcid.org/0000-0002-1566-8156)
- Patrick Koczera
- Th. Seufferlein
Institutions
- Federal Institute for Drugs and Medical Devices (DE)
- Universität Ulm (DE)
- Zimmer Biomet (Germany) (DE)
- University Hospital Ulm (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Pharmacogenomics
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1080/14622416.2025.2510186
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Krebshilfe