Transcription factor E2F1 promotes non-small cell lung cancer progression by activating the PI3K/AKT pathway through MCM4
E2F1 accelerated NSCLC progression by activating the PI3K/AKT pathway through MCM4. Our outcomes confirmed that MCM4 is a potential target for the treatment of NSCLC patients.
Authors
- Yuyin Cai (ORCID: https://orcid.org/0000-0001-5543-5085)
- Lifeng Jiang (ORCID: https://orcid.org/0000-0002-0983-4787)
- Xinyan Lu (ORCID: https://orcid.org/0000-0002-4037-9284)
- Jia Liu (ORCID: https://orcid.org/0000-0001-6711-3841)
- Tingting Li (ORCID: https://orcid.org/0000-0002-6113-1624)
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1186/s13019-025-03481-z
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61