Associations of NEFL gene polymorphisms with neuroblastoma risk in Chinese children from Jiangsu Province

Our findings suggest that <i>NEFL</i> polymorphisms do not significantly modify neuroblastoma susceptibility in this population, suggesting that the previously reported neuroblastoma susceptibility loci in <i>NEFL</i> in Caucasians may not be consistent across different populations. Further research, including larger, more diverse cohorts, is necessary to clarify the potential role of <i>NEFL</i> and other genetic factors in neuroblastoma etiology.

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Publication Details

Journal
Translational Pediatrics
Published
2025-05-01
DOI
https://doi.org/10.21037/tp-2024-611
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of NEFL gene polymorphisms with neuroblastoma risk in Chinese children from Jiangsu Province

Jinhong Zhu, Jiaming Chang, Huanmin Wang, Jing He et al.
Translational Pediatrics
Neuroblastoma Research and Treatments
article

Associations of NEFL gene polymorphisms with neuroblastoma risk in Chinese children from Jiangsu Province

Jinhong Zhu, Jiaming Chang, Huanmin Wang, Jing He, Jiabin Liu, Xiaofeng Chang, Mengzhen Zhang, Chunlei Zhou, Wei Yang
article en

Abstract

Our findings suggest that <i>NEFL</i> polymorphisms do not significantly modify neuroblastoma susceptibility in this population, suggesting that the previously reported neuroblastoma susceptibility loci in <i>NEFL</i> in Caucasians may not be consistent across different populations. Further research, including larger, more diverse cohorts, is necessary to clarify the potential role of <i>NEFL</i> and other genetic factors in neuroblastoma etiology.

Translational PediatricsVol. 14(5)
Harbin Medical University (CN), Capital Medical University (CN), Third Affiliated Hospital of Harbin Medical University (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Beijing Children’s Hospital (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 81%
Neuroblastoma Research and Treatments
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