A CRITICAL CARE PERSPECTIVE ON FAMILIAL MEDITERRANEAN FEVER: CASE REPORT

Familial Mediterranean Fever (FMF) is a rare autosomal recessive autoinflammatory disorder predominantly affecting individuals of Mediterranean origin. FMF is characterized by recurrent febrile episodes and serositis with amyloidosis being its most severe complication, often leading to end-stage renal disease (ESRD). The progression of FMF to amyloidosis is associated with increased morbidity and mortality requiring early diagnosis and effective management. This case report presents a critically ill patient with FMF, amyloidosis and vasculitis-related complications including massive hemorrhage and multi-organ failure. It highlights these complex conditions, the challenges in ICU management and the necessity of a multidisciplinary approach to optimize patients’ outcomes.