Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes
Inositol may counteract PTX resistance in TNBC by disrupting mitochondrial fission, and DWI combined with DKI effectively tracked this effect.
Authors
- Yuanyu Shen (ORCID: https://orcid.org/0000-0002-1782-0924)
- Renhua Wu (ORCID: https://orcid.org/0000-0001-9803-2825)
- Caiyu Zhuang (ORCID: https://orcid.org/0000-0001-7310-0756)
- Wentao Xuan
- Xiaolei Zhang (ORCID: https://orcid.org/0000-0002-5909-5820)
- Yue Chen (ORCID: https://orcid.org/0000-0002-1011-2781)
- Yan Lin (ORCID: https://orcid.org/0000-0002-8284-9029)
- Lixin Ke (ORCID: https://orcid.org/0009-0008-1547-9532)
- Wen Li (ORCID: https://orcid.org/0000-0002-4801-727X)
- Zhiliang Ye
- Shiyan Xie
Institutions
- Shantou University (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1186/s13058-025-02051-4
- Citations
- 2
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province