Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults

Background: Among the different forms of obesity, abdominal obesity has shown particularly strong associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults. Method: This cross-sectional, multicenter study was carried out at Isra University Hospital, Memon Medical Complex, and Rajputana Hospital in Hyderabad between April 2021 and July 2024. 376 Young adults within the age bracket of 18-35 years, both males and females, were recruited in the study via convenience sampling technique. The anthropometric measurements of participants were measured. Afterward, fasting blood samples were collected for biochemical analysis. Lipid profiles were assessed using the Microlab 300 machine. The data collected from respondents were entered and analyzed using MedCalc Statistical Software. The Pearson correlation test was applied to measure the strength of the association between variables. P level <0.05 was considered significant. Results: The mean age of participants was 29.45±3.1 years. The study revealed significant negative correlations between LDL (r = -0.49, p = 0.001), VLDL (r = -0.42, p = 0.01), total cholesterol (r = -0.51, p = 0.03), hemoglobin (r = -0.31, p < 0.001), and WBC count (r = -0.49, p = 0.001) with lung function parameters. Conversely, HDL cholesterol was positively correlated with FEV1 (r = 0.34, p = 0.00), while platelet and RBC counts showed weak, mostly non-significant associations. Conclusion: The findings suggest a fair to moderate correlation between hematological and lipid profile parameters with respiratory functions in class I obese young adults.