RNA Technologies in Cancer Care: Bridging Promise and Practice

RNA technologies are rapidly reshaping cancer diagnostics and therapeutics, offering unprecedented promise alongside persistent challenges. This News and Views synthesizes evidence from meta-analyses and systematic reviews on RNA sequencing (RNA-seq), non-coding RNAs, and RNA-based therapies. We highlight advances in personalized diagnostics, mRNA vaccines, and RNA interference (RNAi), while addressing technical, clinical, and ethical barriers to clinical adoption. A balanced perspective is essential as the field advances toward precision oncology.