Mycoplasma pneumoniae-Induced Rash and Mucositis (MIRM): A Case Report

This case report describes a 27-year-old military serviceman in Saudi Arabia who developed severe mucocutaneous lesions - oral and genital ulcers, conjunctivitis, and eruptive rash - following an upper respiratory infection. Initially, his clinical presentation raised suspicion of Behçet's disease; however, further evaluation and investigation favored Mycoplasma pneumoniae-induced rash and mucositis (MIRM) as a final diagnosis. His management included antibiotics and systemic corticosteroids, leading to marked clinical improvement. This case report highlights the diagnostic challenges of MIRM, particularly in regions where it is underreported. It underlines the importance of considering MIRM in patients with mucocutaneous eruptions, even without classic respiratory findings. By sharing this experience, we are aiming to enhance awareness of MIRM features and facilitate timely diagnosis. The patient's recovery also supports MIRM's generally favorable prognosis with appropriate treatment.

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Publication Details

Journal
Cureus
Published
2025-05-28
DOI
https://doi.org/10.7759/cureus.84964
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Mycoplasma pneumoniae-Induced Rash and Mucositis (MIRM): A Case Report

Hussni O. Mohammed, Hind I. Shaheen, Moneerah A AlGassim, Mohanned M Alraddadi et al.
Cureus
Drug-Induced Adverse Reactions
article

Mycoplasma pneumoniae-Induced Rash and Mucositis (MIRM): A Case Report

Hussni O. Mohammed, Hind I. Shaheen, Moneerah A AlGassim, Mohanned M Alraddadi, Reem H Al-Ruwaili
article en

Abstract

This case report describes a 27-year-old military serviceman in Saudi Arabia who developed severe mucocutaneous lesions - oral and genital ulcers, conjunctivitis, and eruptive rash - following an upper respiratory infection. Initially, his clinical presentation raised suspicion of Behçet's disease; however, further evaluation and investigation favored Mycoplasma pneumoniae-induced rash and mucositis (MIRM) as a final diagnosis. His management included antibiotics and systemic corticosteroids, leading to marked clinical improvement. This case report highlights the diagnostic challenges of MIRM, particularly in regions where it is underreported. It underlines the importance of considering MIRM in patients with mucocutaneous eruptions, even without classic respiratory findings. By sharing this experience, we are aiming to enhance awareness of MIRM features and facilitate timely diagnosis. The patient's recovery also supports MIRM's generally favorable prognosis with appropriate treatment.

CureusVol. 17(5)
King Fahd Medical City (SA), Sion College (GB), Ibn Sina Hospital (KW)
Zero hunger
Openalex Percentile: Top 86%
Drug-Induced Adverse Reactions
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Mycoplasma pneumoniae-Induced Rash and Mucositis (MIRM): A Case Report — Hussni O. Mohammed, Hind I. Shaheen, et al. · Cureus (2025) | TGRS Research Map | TGRS