Clinical case of somatotropinoma in a patient with morbid obesity

Obesity is a chronic endocrine disorder characterized by excessive adipose tissue and associated with development of various adverse metabolic processes in the body. This case report highlights a clinical case involving the detection of a hormonally active pituitary microadenoma in a patient with morbid obesity and reproductive dysfunction. The application of a described multidisciplinary approach led to the timely verification of the underlying condition and the routing of the patient to a specialized center, which prevented the development of complications associated with acromegaly and improved the patient’s quality of life. Restoration of cyclic ovarian function following neurosurgical intervention and regression of adipose mass resulted in clinical improvement of well-being and the occurrence of pregnancy. Currently, the patient is under the care and observation of a multidisciplinary team of specialists.

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Publication Details

Journal
Obesity and metabolism
Published
2025-05-24
DOI
https://doi.org/10.14341/omet13103
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical case of somatotropinoma in a patient with morbid obesity

R. M. Guseinova, Vilen Azizyan, A. A. Averkina, Е. Н. Андреева et al.
Obesity and metabolism
Pituitary Gland Disorders and Treatments
article

Clinical case of somatotropinoma in a patient with morbid obesity

R. M. Guseinova, Vilen Azizyan, A. A. Averkina, Е. Н. Андреева, A. V. Dorovskikh, O. V. Vasyukova, E. V. Bondarenko, D. A. Kopytina, Manushak Rafaelyan, Н. Г. Мокрышева, Е А Пигарова
article en

Abstract

Obesity is a chronic endocrine disorder characterized by excessive adipose tissue and associated with development of various adverse metabolic processes in the body. This case report highlights a clinical case involving the detection of a hormonally active pituitary microadenoma in a patient with morbid obesity and reproductive dysfunction. The application of a described multidisciplinary approach led to the timely verification of the underlying condition and the routing of the patient to a specialized center, which prevented the development of complications associated with acromegaly and improved the patient’s quality of life. Restoration of cyclic ovarian function following neurosurgical intervention and regression of adipose mass resulted in clinical improvement of well-being and the occurrence of pregnancy. Currently, the patient is under the care and observation of a multidisciplinary team of specialists.

Obesity and metabolismVol. 22(1)
Endocrinology Research Center (RU)
Openalex Percentile: Top 83%
Pituitary Gland Disorders and Treatments
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Clinical case of somatotropinoma in a patient with morbid obesity — R. M. Guseinova, Vilen Azizyan, et al. · Obesity and metabolism (2025) | TGRS Research Map | TGRS