AttenCRF-U: Joint Detection of Sleep-Disordered Breathing and Leg Movements in OSA Patients

Obstructive sleep apnea (OSA) is characterized by frequent episodes of sleep-disordered breathing (SDB), which are often accompanied by leg movement (LM) events, especially periodic limb movements during sleep (PLMS). Traditional single-event detection methods often overlook the dynamic interactions between SDB and LM, failing to capture their temporal overlap and differences in duration. To address this, we propose Attention-enhanced CRF with U-Net (AttenCRF-U), a novel joint detection framework that integrates multi-head self-attention (MHSA) within an encoder-decoder architecture to model long-range dependencies between overlapping events and employs multi-scale convolutional encoding to extract discriminative features across different temporal scales. The model further incorporates a conditional random field (CRF) to refine event boundaries and enhance temporal continuity. Evaluated on clinical PSG recordings from 125 OSA patients, the model with CRF improved the average F1 score from 0.782 to 0.788 and reduced temporal alignment errors compared with CRF-free baselines. The joint detection strategy distinguished respiratory-related leg movements (RRLMs) from PLMS, boosting the PLMS detection F1 score from 0.756 to 0.778 and the SDB detection F1 score from 0.709 to 0.728. By integrating MHSA into a CRF-augmented U-Net framework and enabling joint detection of multiple event types, this study presents a novel approach to modeling temporal dependencies and event co-occurrence patterns in sleep disorder diagnosis.

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Publication Details

Journal
Bioengineering
Published
2025-05-26
DOI
https://doi.org/10.3390/bioengineering12060571
Citations
1
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
1.16
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article

AttenCRF-U: Joint Detection of Sleep-Disordered Breathing and Leg Movements in OSA Patients

Yiyuan Zhang, Qiu‐Yue Li, Wei Chen, Chen Chen et al.
1 citations
Bioengineering
Obstructive Sleep Apnea Research
1.16
article

AttenCRF-U: Joint Detection of Sleep-Disordered Breathing and Leg Movements in OSA Patients

Yiyuan Zhang, Qiu‐Yue Li, Wei Chen, Chen Chen, Huan Yu, Cong Fu, Kewei Li
article en
1 citations

Abstract

Obstructive sleep apnea (OSA) is characterized by frequent episodes of sleep-disordered breathing (SDB), which are often accompanied by leg movement (LM) events, especially periodic limb movements during sleep (PLMS). Traditional single-event detection methods often overlook the dynamic interactions between SDB and LM, failing to capture their temporal overlap and differences in duration. To address this, we propose Attention-enhanced CRF with U-Net (AttenCRF-U), a novel joint detection framework that integrates multi-head self-attention (MHSA) within an encoder-decoder architecture to model long-range dependencies between overlapping events and employs multi-scale convolutional encoding to extract discriminative features across different temporal scales. The model further incorporates a conditional random field (CRF) to refine event boundaries and enhance temporal continuity. Evaluated on clinical PSG recordings from 125 OSA patients, the model with CRF improved the average F1 score from 0.782 to 0.788 and reduced temporal alignment errors compared with CRF-free baselines. The joint detection strategy distinguished respiratory-related leg movements (RRLMs) from PLMS, boosting the PLMS detection F1 score from 0.756 to 0.778 and the SDB detection F1 score from 0.709 to 0.728. By integrating MHSA into a CRF-augmented U-Net framework and enabling joint detection of multiple event types, this study presents a novel approach to modeling temporal dependencies and event co-occurrence patterns in sleep disorder diagnosis.

BioengineeringVol. 12(6)
The University of Sydney (AU), Fudan University (CN), Pudong Medical Center (CN), Huashan Hospital (CN)
Openalex Percentile: Top 22%
Obstructive Sleep Apnea Research
1.16
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