Misdiagnosed as a "High-Need Baby": Delayed Diagnosis of Cow’s Milk Protein Allergy in an Exclusively Breastfed Infant

Background: The term "high-need baby" has gained popularity among parents and on social media, but lacks clinical recognition. This non-medical label can delay the diagnosis of underlying medical conditions. Case Presentation: We report the case of a 7-month-old exclusively breastfed infant with persistent irritability and sleep disturbances, diagnosed by his pediatrician as a "high-need baby." Clinical evaluation revealed symptoms compatible with cow’s milk protein allergy (CMPA). Elimination of dairy from the maternal diet led to full symptom resolution. A subsequent oral challenge confirmed the diagnosis. Conclusion: This case illustrates the importance of maintaining clinical rigor when evaluating persistent infant symptoms and avoiding reliance on non-medical labels such as “high-need baby.”

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Publication Details

Journal
International Journal of Clinical Case Reports and Reviews
Published
2025-05-15
DOI
https://doi.org/10.31579/2690-4861/783
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Misdiagnosed as a "High-Need Baby": Delayed Diagnosis of Cow’s Milk Protein Allergy in an Exclusively Breastfed Infant

Martin esteban Gruenberg
International Journal of Clinical Case Reports and Reviews
Food Allergy and Anaphylaxis Research
article

Misdiagnosed as a "High-Need Baby": Delayed Diagnosis of Cow’s Milk Protein Allergy in an Exclusively Breastfed Infant

Martin esteban Gruenberg
article en

Abstract

Background: The term "high-need baby" has gained popularity among parents and on social media, but lacks clinical recognition. This non-medical label can delay the diagnosis of underlying medical conditions. Case Presentation: We report the case of a 7-month-old exclusively breastfed infant with persistent irritability and sleep disturbances, diagnosed by his pediatrician as a "high-need baby." Clinical evaluation revealed symptoms compatible with cow’s milk protein allergy (CMPA). Elimination of dairy from the maternal diet led to full symptom resolution. A subsequent oral challenge confirmed the diagnosis. Conclusion: This case illustrates the importance of maintaining clinical rigor when evaluating persistent infant symptoms and avoiding reliance on non-medical labels such as “high-need baby.”

International Journal of Clinical Case Reports and ReviewsVol. 25(05)
Sleep Research Society (US)
Openalex Percentile: Top 82%
Food Allergy and Anaphylaxis Research
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