Eyelid Basal Cell Carcinoma with Orbital Invasion Successfully Treated with Definitive Radiotherapy: a Case Report

Basal cell carcinoma of eyelid with orbital invasion are usually treated with demolitive surgery leading to severe morbidity and poor quality of life. A multidisciplinary approach is today mandatory in order to choose the best treatment or a combination of them. Radiotherapy could be a valid option in these patients, both definitive and postoperative in case of risk factors. We describe a case report of an elderly patient with locally advanced basal cell carcinoma, that refused orbital exenteration. After imaging evaluation and treatment planning, she was treated with exclusive external beam radiotherapy (EBRT) at 54 Gy, with complete response at one year follow up, with only mild toxicity: she presented mild inferior palpebral retraction and mild keratoconjunctivitis sicca, not affecting daily quality of life. EBRT could be always considered in the multidisciplinary approach to eyelid and orbital tumors, to better personalize multimodality treatment.