Prevalence of Plasmodium falciparum parasites with pfhrp2 exon 2 gene deletion in symptomatic malaria patients across Ghana in 2021
No false negative sample was identified in this study, and less than 1% of parasites with pfhrp2 gene deletions (mainly from RDT positive samples) were found in the population . This finding offers assurance for the continued reliance on HRP2-based RDTs for malaria screening in public health clinics in Ghana. Nonetheless, continued surveillance is needed to determine the expansion of P. falciparum with these gene deletions.
Authors
- Sebastian Shine Kwapong
- George Asumah Adu (ORCID: https://orcid.org/0000-0001-8412-7954)
- Martin Chamai (ORCID: https://orcid.org/0000-0001-7149-1810)
- Nana Yaw Peprah (ORCID: https://orcid.org/0000-0003-1633-7911)
- Keziah Lawrencia Malm (ORCID: https://orcid.org/0000-0003-0190-0820)
- Linda Eva Amoah (ORCID: https://orcid.org/0000-0002-1652-8489)
- Dorcas Bredu (ORCID: https://orcid.org/0000-0003-4863-4259)
- Benjamin Abuaku (ORCID: https://orcid.org/0000-0002-1840-6979)
- Sherik-fa Anang
- Prosper Kofi Tey
- Bernice Cubbson Abban
- Alexander Asamoah
- Eunice Obeng Amoako
Institutions
- University of Ghana (GH)
- Noguchi Memorial Institute for Medical Research (GH)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1186/s12936-025-05419-1
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Global Fund to Fight AIDS, Tuberculosis and Malaria
- University of Ghana
- Noguchi Memorial Institute for Medical Research, University of Ghana