Lhermitte-Duclos Disease Recovery After Subtotal Resection; Case Report

Lhermitte-Duclos Disease (LDD) is a rare benign hamartomatous disorder that typically manifests unilaterally in the cerebellum, leading to thickening of the molecular and granular cell layers of the cerebellar cortex. It most commonly occurs in young adulthood, typically in the third or fourth decade of life. Since LDD is a slowly progressive disease, conservative management is an option in the absence of mass effect, whereas total excision is recommended in symptomatic patients. In our case, subtotal resection was performed due to indistinct surgical margins observed intraoperatively. Postoperative cranial magnetic resonance imaging (MRI) demonstrated regression of the lesion. No recurrence or residual tumor was detected at the 7-month follow-up. During this period, the patient remained neurologically stable without newly developed symptoms or deficits. However, long-term follow-up is essential to monitor for potential recurrence.