Treatment pathways of lipid-lowering therapies in Germany 2016–2022

Changes in LLT were only observed in a minority of patients. BA and PCSK9i were switched more frequently than statins and ezetimibe. BA was discontinued earlier, and PCSK9i later than the other agents. Continued efforts to maintain long-term adherence and overcome therapeutic inertia are needed to realise the potential of available LLT with proven cardiovascular benefit.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2025-05-28
DOI
https://doi.org/10.1007/s00392-025-02686-5
Citations
4
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
8.03

Funders

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article

Treatment pathways of lipid-lowering therapies in Germany 2016–2022

Beate Leppert, Martin Schulz, Ulrich Laufs, Claudia Grellmann et al.
4 citations
Clinical Research in Cardiology
Lipoproteins and Cardiovascular Health
8.03
article

Treatment pathways of lipid-lowering therapies in Germany 2016–2022

Beate Leppert, Martin Schulz, Ulrich Laufs, Claudia Grellmann, Julius L. Katzmann, Irina Müller-Kozarez
article en
4 citations

Abstract

Changes in LLT were only observed in a minority of patients. BA and PCSK9i were switched more frequently than statins and ezetimibe. BA was discontinued earlier, and PCSK9i later than the other agents. Continued efforts to maintain long-term adherence and overcome therapeutic inertia are needed to realise the potential of available LLT with proven cardiovascular benefit.

Clinical Research in CardiologyVol. 115(2)
Ingenieurgesellschaft Auto und Verkehr (Germany) (DE), Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie (DE), University Hospital Leipzig (DE), Klinik und Poliklinik für Neurologie (DE), Freie Universität Berlin (DE)
Daiichi-Sankyo, Daiichi Sankyo Europe
Good health and well-being
Openalex Percentile: Top 3%
Lipoproteins and Cardiovascular Health
8.03
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Treatment pathways of lipid-lowering therapies in Germany 2016–2022 — Beate Leppert, Martin Schulz, et al. · Clinical Research in Cardiology (2025) | TGRS Research Map | TGRS