Pediatric cancer registry in Turkey 2002-2024 (TPOG and TPHD): The data from the last 23 years.

e22012 Background: Each year more than 400.000 new pediatric cancer cases are expected in children and adolescents aged 0-14 globally. The improvement of the survival rates in low and middle-income countries (LMICs) is on the global cancer control agenda and the cancer registry is an essential element of pediatric cancer control. The results of the 23 years of the pediatric cancer registry from Turkey is presented here. Methods: Turkish Pediatric Oncology Group and Turkish Pediatric Hematology Association has established the pediatric cancer registry in 2002. The childhood cancer cases registered between 2002-2024 was included in this analysis. International Childhood Cancer Classification System was used for the classification. Essential demographic findings, ICD-O-3 morphology and topography codes were recorded for each case. Results: During the 23 years from 2002 to 2024, 52907 cases were registered. For all cases, median age was 6.6 year (0-19; M/F 29799/23094, 7 hermaphrodit, 7 unknown). Age distribution was 0-4 yrs, 40.9%; 5-9 yrs, 24.7%; 10-14 yrs, 23.2%; 15-19 yrs, 11.1%) The distribution of the tumor types were [number of cases, percentage of total, median age yrs, M/F]: Leukemia (15184, 28.7%, 5.6, 8846/6338); Lymphoma & other RES tumors (9262, 17.5%, 9.3, 6148/3112, 2 unknown); CNS [brain & spinal] (7648, 14.5%, 7.0, 4265/3382, 1 unknown); Symphatetic system (3910, 7.4%, 2.4, 2018/1891, 1 hermaphrodite); Retinoblastoma (1518, 2.9%, 1.5, 803/715); Renal (2397, 4.5%, 3.1, 1184/1210, 2 hermaphrodite & 1 unknown); Liver (747, 1.4%, 2.1, 440/307); Malignant bone (3277, 6.2%, 12.5, 1840/1437); Soft tissue sarcomas (3806, 7.2%, 7.4, 2113/1693); Germ cell (3042, 5.7%, 9.0, 1119/1916, 4 hermaphrodite, 3 unknown); Carcinoma& other malignant epithelial (1731, 3.3%, 13.1, 829/902); Other/non-specific malignant (385, 0.7%, 7.8, 194/191). Five-year survival rate was found as 70.9%. Conclusions: The survival rates for children and adolescents have been improved to 70% which is comparable for middle-income countries and reflects the level of the pediatric cancer care in Turkey. With the record of cases during the last 23 years, It became a valuable source for stakeholders in national and international level.