High Prevalence of Artemisinin-Resistant <i>Plasmodium falciparum</i>, Southeastern Sudan

We conducted a hospital-based cross-sectional study of Plasmodium falciparum in 2017 in southeastern Sudan. Among 257 P. falciparum samples, we found 22% harbored the pfkelch13 R622I mutation and 10.7% showed hrp2/3 gene deletions. Our findings highlight the urgent need for enhanced surveillance of drug- and diagnostic-resistant parasites in the Horn of Africa.

Authors

Publication Details

Journal
Emerging infectious diseases
Published
2025-05-28
DOI
https://doi.org/10.3201/eid3106.241810
Citations
1
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
1.88
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High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan

Carlo Severini, Lucien Platon, Bakri Y. M. Nour, Laurence Ma et al.
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Emerging infectious diseases
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High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan

Carlo Severini, Lucien Platon, Bakri Y. M. Nour, Laurence Ma, Lemu Golassa, Edvige Perrotti, Albadawi Abdelbagi Talha, Mariangela L’Episcopia, Didier Ménard, Emmanuelle Caspar, Lucas Thiebaut, Ibrahim Mohamed Ahmed Sana, Buze Chala
article en
1 citations

Abstract

We conducted a hospital-based cross-sectional study of Plasmodium falciparum in 2017 in southeastern Sudan. Among 257 P. falciparum samples, we found 22% harbored the pfkelch13 R622I mutation and 10.7% showed hrp2/3 gene deletions. Our findings highlight the urgent need for enhanced surveillance of drug- and diagnostic-resistant parasites in the Horn of Africa.

Emerging infectious diseasesVol. 31(6)
Openalex Percentile: Top 15%
Malaria Research and Control
1.88
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