Uveitis in Adults

Uveitis is characterized by inflammation of the uvea and primarily affects adults aged 20 to 50 years. For noninfectious anterior uveitis, corticosteroid eyedrops are first-line treatment. For posterior noninfectious uveitis, disease-modifying antirheumatic drugs are first-line therapy; biologics such as adalimumab are second-line treatment for patients with inflammation refractory to treatment. Uveitis caused by systemic infection should be treated with antimicrobials, and local or systemic steroids may be used depending on the severity of uveitis and the specific microorganism.

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Publication Details

Journal
JAMA
Published
2025-05-28
DOI
https://doi.org/10.1001/jama.2025.4358
Citations
30
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
51.21
Controls
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article

Uveitis in Adults

Panagiotis Maghsoudlou, Andrew D. Dick, Simon Epps, Catherine Guly
30 citations
JAMA
Ocular Diseases and Behçet’s Syndrome
51.21
article

Uveitis in Adults

Panagiotis Maghsoudlou, Andrew D. Dick, Simon Epps, Catherine Guly
article en
30 citations

Abstract

Uveitis is characterized by inflammation of the uvea and primarily affects adults aged 20 to 50 years. For noninfectious anterior uveitis, corticosteroid eyedrops are first-line treatment. For posterior noninfectious uveitis, disease-modifying antirheumatic drugs are first-line therapy; biologics such as adalimumab are second-line treatment for patients with inflammation refractory to treatment. Uveitis caused by systemic infection should be treated with antimicrobials, and local or systemic steroids may be used depending on the severity of uveitis and the specific microorganism.

JAMAVol. 334(5)
University of Bristol (GB), NIHR Moorfields Biomedical Research Centre (GB), Bristol Eye Hospital (GB), University College London (GB)
No poverty
Openalex Percentile: Top 0%
Ocular Diseases and Behçet’s Syndrome
51.21
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