Uveitis in Adults
Uveitis is characterized by inflammation of the uvea and primarily affects adults aged 20 to 50 years. For noninfectious anterior uveitis, corticosteroid eyedrops are first-line treatment. For posterior noninfectious uveitis, disease-modifying antirheumatic drugs are first-line therapy; biologics such as adalimumab are second-line treatment for patients with inflammation refractory to treatment. Uveitis caused by systemic infection should be treated with antimicrobials, and local or systemic steroids may be used depending on the severity of uveitis and the specific microorganism.
Authors
- Panagiotis Maghsoudlou (ORCID: https://orcid.org/0000-0002-9945-3901)
- Andrew D. Dick
- Simon Epps
- Catherine Guly
Institutions
- University of Bristol (GB)
- NIHR Moorfields Biomedical Research Centre (GB)
- Bristol Eye Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- JAMA
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1001/jama.2025.4358
- Citations
- 30
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 51.21