Sticky Platelet Syndrome: An important consideration for otherwise unexplained thrombotic events in young stroke patients
Thrombosis in unusual sites and despite anticoagulant use, coupled with platelet hyperactivity to ADP, were suggestive of Sticky Platelet Syndrome. Due to lack of testing standardization, diagnosis of a persistent, hyperreactive platelet phenotype remains challenging. However, improvements in diagnostic approaches for Sticky Platelet Syndrome can be highly beneficial in enabling faster treatment with an appropriate antithrombotic regimen, reducing the risk of subsequent thrombotic events.
Authors
- Charity Gorospe
- Benedict Pereira
- Shlee Song (ORCID: https://orcid.org/0000-0002-7838-0205)
- Jcm Ho (ORCID: https://orcid.org/0000-0003-4499-5284)
- Arun Shriram
- Alexis N. Simpkins (ORCID: https://orcid.org/0000-0001-7529-4267)
- Azam Elahi (ORCID: https://orcid.org/0000-0003-0539-4224)
- Cindy Rivas
- Diana Yang
- Yu Ran Lee
Institutions
- Cedars-Sinai Medical Center (US)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108364
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb Foundation
- National Institute on Aging