Hydronephrosis-Associated Renal Fibrosis: Clinical Validation of Spp1 as a Biomarker and Therapeutic Target
Spp1 is a critical mediator in renal fibrosis and a promising biomarker for assessing hydronephrosis severity. Its diagnostic value, particularly when combined with U-TRF, underscores the need for further research into Spp1-targeted therapies in renal fibrosis.
Authors
- Guang Chen (ORCID: https://orcid.org/0000-0003-3493-2810)
- W. Shan
- Wenqing Li (ORCID: https://orcid.org/0009-0000-6591-9059)
- Jidong Chen (ORCID: https://orcid.org/0000-0002-4040-6350)
- Xiao Wang (ORCID: https://orcid.org/0000-0001-8824-6280)
- Hui Li
- Jun Zhou (ORCID: https://orcid.org/0000-0001-5822-8233)
Institutions
- Fuyang City People's Hospital (CN)
- Fuyang Maternity and Child Health Care Hospital (CN)
- Fuyang Second People's Hospital (CN)
Publication Details
- Journal
- Kidney & Blood Pressure Research
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1159/000546465
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Medical University
- Fuyang Normal University