Chloride Mass Transfers during Continuous Veno-Venous Hemodialysis with Regional Citrate Anticoagulation: Effects of Additional Ultrafiltration and Hamburger’s Effect
Plasma chloride mass removal during CVVHD-RCA is significantly greater than what is accounted for by dialysate-based loss, suggesting that plasma chloride is transferred to an intracellular compartment. Furthermore, to account for the online administration of citrate and CaCl<sub>2</sub> solutions, CVVHD-RCA applies additional ultrafiltration, which significantly contributes to chloride removal from plasma water.
Authors
- Rinaldo Bellomo (ORCID: https://orcid.org/0000-0002-1650-8939)
- Laurent Bitker (ORCID: https://orcid.org/0000-0002-4698-053X)
- Guillaume Deniel (ORCID: https://orcid.org/0000-0002-4006-6114)
- Jean-Christophe Richard (ORCID: https://orcid.org/0000-0003-1503-3035)
- Matthieu Chivot
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Austin Hospital (AU)
- Hôpital de la Croix-Rousse (FR)
- Hospices Civils de Lyon (FR)
- Institut National des Sciences Appliquées de Lyon (FR)
Publication Details
- Journal
- Blood Purification
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1159/000546322
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00