Activity of the default mode network mediates the effect of peripheral plasma glial cell line-derived neurotrophic factor levels on rumination in major depressive disorder patients
In MDD patients, GDNF levels were associated with neural activity within the DMPFC subsystem of the DMN, which statistically mediated the link to rumination severity.
Authors
- Xiaoqian Fu (ORCID: https://orcid.org/0000-0003-0753-2168)
- Chao‐Gan Yan (ORCID: https://orcid.org/0000-0003-3413-5977)
- Chuansheng Quan
- Xingran Wang (ORCID: https://orcid.org/0000-0003-0313-2810)
- Yuan Zhou (ORCID: https://orcid.org/0000-0001-6378-1711)
- Hongyan Sun
- Jing Ruan (ORCID: https://orcid.org/0000-0001-9775-6186)
- Yan Wang (ORCID: https://orcid.org/0000-0002-2277-7115)
- Xiangdong Du
- Xiao Chen (ORCID: https://orcid.org/0000-0001-5561-6572)
- Lili Liu (ORCID: https://orcid.org/0000-0002-1237-1568)
- Fennan Jia
- Yan-Song Liu
- Yue‐Xiang Huang
Institutions
- Chinese Academy of Sciences (CN)
- Soochow University (CN)
- Zhangjiagang First People's Hospital (CN)
- Suzhou Guangji Hospital (CN)
- Institute of Genetics and Developmental Biology (CN)
- Institute of Psychology, Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Psychoradiology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/psyrad/kkaf014
- Citations
- 2
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Natural Science Foundation of Jiangsu Province
- Science and Technology Program of Suzhou