Galectin-1 expression in breast cancer stroma – prognostic value in triple-negative breast cancer

The immunosuppressive effects of galectin-1 forming a shield around tumor nests may form an immune escape mechanism and can explain the worse OS and PFS we found in TNBC. Owing to the exploratory nature of the study, the results need confirmation in order to investigate the potentials of anti-galectin-1 therapies.

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Publication Details

Journal
Pathobiology
Published
2025-05-28
DOI
https://doi.org/10.1159/000546206
Citations
1
Primary Topic
Galectins and Cancer Biology
Type
article
Field-Weighted Citation Impact
0.80
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article

Galectin-1 expression in breast cancer stroma – prognostic value in triple-negative breast cancer

László Krenács, Gábor Cserni, Szintia Almási, Tibor Krenács
1 citations
Pathobiology
Galectins and Cancer Biology
0.80
article

Galectin-1 expression in breast cancer stroma – prognostic value in triple-negative breast cancer

László Krenács, Gábor Cserni, Szintia Almási, Tibor Krenács
article en
1 citations

Abstract

The immunosuppressive effects of galectin-1 forming a shield around tumor nests may form an immune escape mechanism and can explain the worse OS and PFS we found in TNBC. Owing to the exploratory nature of the study, the results need confirmation in order to investigate the potentials of anti-galectin-1 therapies.

PathobiologyVol. 92(6)
Semmelweis University (HU), University of Szeged (HU), Bács-Kiskun Megyei Kórház (HU)
Good health and well-being
Openalex Percentile: Top 28%
Galectins and Cancer Biology
0.80
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