Occurrence of vanA/vanM-positive vancomycin-resistant Enterococcus faecium in hospital wastewater associated with clinical infections in Guangzhou, China: A genomic epidemiological study
Hospital wastewater is a critical reservoir for high-risk VREfm clones, particularly the outbreak-associated ST80 lineage. The persistence of VREfm in effluents and evidence of cross-source transmission underscores the urgent need for enhanced environmental surveillance. Integrated strategies addressing environmental reservoirs are essential to combat the growing threat of VREfm.
Authors
- Yuqi Hong
- Cong Shen (ORCID: https://orcid.org/0000-0003-2677-3960)
- Meina Wu (ORCID: https://orcid.org/0000-0002-3645-6494)
- Xiaoyue Zhang (ORCID: https://orcid.org/0009-0005-6161-6292)
- Xinying Zeng (ORCID: https://orcid.org/0000-0002-0963-5155)
- Shaowei Meng
- Jingwei Lin (ORCID: https://orcid.org/0000-0002-2476-9928)
- Shu‐Yi Huang
- Hao Wu (ORCID: https://orcid.org/0000-0003-1269-7354)
- Yuxing Zhang (ORCID: https://orcid.org/0000-0003-4469-8837)
- Bangjie Yang
- Chen Cha (ORCID: https://orcid.org/0000-0001-7297-2202)
- Zhongde Zhang (ORCID: https://orcid.org/0000-0002-8958-3251)
- Xuan Zhang (ORCID: https://orcid.org/0009-0001-9856-1812)
- Shijia Yu
- Lingqing Xu (ORCID: https://orcid.org/0000-0002-6451-1673)
- Xue Ao (ORCID: https://orcid.org/0000-0002-4724-5393)
- Liling Zhang
- Mingshen Su
- Yueting Jiang
- Ni Zhang (ORCID: https://orcid.org/0009-0005-0130-2240)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Kunming Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Journal of Medical Microbiology
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1016/j.ijmm.2025.151658
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00