Association of cardiometabolic multimorbidity with postoperative delirium and three-year mortality in patients undergoing knee/hip arthroplasty: a prospective cohort study
CMM may be a risk factor for POD, with CSF T-tau potentially playing a mediating role. These findings underscore the importance of preoperative cognitive assessment for risk stratification and suggest CSF T-tau as a potential intervention target. Future studies may further explore intervention strategies targeting CMM and CSF T-tau.
Authors
- Aihua Zhang (ORCID: https://orcid.org/0000-0001-6398-1318)
- Hongyan Gong
- Jiahan Wang (ORCID: https://orcid.org/0009-0006-5115-6939)
- Wenjie Kong
- Lin Xu (ORCID: https://orcid.org/0000-0002-0537-922X)
- Bin Wang (ORCID: https://orcid.org/0000-0002-6159-5242)
- Kun Wang (ORCID: https://orcid.org/0000-0001-9851-7080)
- Yizhi Liang (ORCID: https://orcid.org/0000-0002-7475-496X)
- Yanan Lin
- Yanlin Bi (ORCID: https://orcid.org/0000-0002-9006-976X)
- Yuanlong Wang (ORCID: https://orcid.org/0009-0009-1022-5581)
- Chuan Li (ORCID: https://orcid.org/0000-0001-8098-1715)
Institutions
- Qingdao University (CN)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1097/js9.0000000000002379
- Citations
- 1
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.55