Evaluating the Efficacy of Vitamin C Injections in Curing Gingival Disease - A Clinical Trial

Periodontal disease involves gingival inflammation and tissue damage, often influenced by nutritional factors. Vitamin C, vital for collagen synthesis and immune support, is linked to gingival health, with deficiencies causing periodontal issues. This study explores the efficacy of vitamin C injections as a potential treatment modality to enhance periodontal outcomes. A descriptive, cross-sectional study was involving total of 10 participants reporting to out-patient Department of Periodontics. Each patient received two intramucosal injections of 200–300 mg of vitamin C(ASCORMIT®), administered on day 0 and day 7. The GBI, PI, probing depth, and VAS scores were recorded at baseline, week 1 and 4 to monitor changes over time. Statistical analyses were conducted to determine the significance of improvements in these parameters. The study showed significant reductions in GBI, PI, and probing depth, indicating improved gingival health and periodontal healing. Participants reported reduced discomfort via VAS. By week 4, GBI decreased from 2.5 to 0.8, PI from 3.2 to 1.2, probing depth from 4.5 mm to 3.0 mm, and VAS scores from 6.8 to 2.1, supporting vitamin C injections as an adjunctive gingival disease treatment. Vitamin C injections proved highly effective in improving periodontal health by significantly reducing inflammation, enhancing tissue healing, and supporting overall gum regeneration. These positive results highlight the potential of vitamin C injections as a powerful adjunctive therapy, offering a promising advancement in the management of periodontal disease. Key Words: Gingival Disease, Gingivitis, Intramucosal Injections, Periodontal Health Vitamin C