MIF regulates T helper 17 cell differentiation by activating the p38 MAPK signaling pathway to drive the pathogenesis of EAP
The results of the present study revealed that the MIF/CD74/CD44 axis played a critical role in Th17 cell differentiation via the p38 MAPK pathway in CNP. Thus, targeting the MIF/CD74/CD44/p38 MAPK pathway may offer a novel therapeutic strategy for treating chronic prostatitis.
Authors
- Jialin Meng (ORCID: https://orcid.org/0000-0002-4622-833X)
- Yan Xu (ORCID: https://orcid.org/0000-0002-7919-4762)
- Chang Yin Liang (ORCID: https://orcid.org/0000-0003-2317-1323)
- Song Zhang (ORCID: https://orcid.org/0000-0002-5976-5054)
- Meng Zhang (ORCID: https://orcid.org/0000-0003-4935-4005)
- Jin Chen (ORCID: https://orcid.org/0000-0001-6076-1141)
- Rui Feng (ORCID: https://orcid.org/0000-0003-4151-7228)
- Meng Tong (ORCID: https://orcid.org/0000-0003-4832-2490)
- Cheng Yang (ORCID: https://orcid.org/0000-0002-6969-1968)
- Fei Zhang (ORCID: https://orcid.org/0000-0001-6147-6131)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1016/j.intimp.2025.114959
- Citations
- 3
- Primary Topic
- Macrophage Migration Inhibitory Factor
- Type
- article
- Field-Weighted Citation Impact
- 2.39