Oligostilbenoids and Phenolic Compounds from The Stem Bark of Shorea materialis RIDL. (Dipterocarpaceae)

The Shorea genus is known for its abundance of sources of oligostilbenoids, which exhibit diverse biological functions. Nevertheless, despite its considerable potential, there remains a dearth of phytochemical investigations including Shorea materialis. Consequently, this study aims to isolate the chemical constituents from the stem bark of this species. The crude extract of S. materialis was obtained from the maceration technique and fractionation using vacuum liquid chromatography. The resulting fractions were further purified via column chromatography. The molecular structures of the isolated molecules were determined using various spectroscopic techniques. Two dimer stilbenoids, ampelopsins A (1) and D (2), three trimers, namely α-viniferin (3), hopeanolin (4) and davidiol A (5), one tetramer, vaticanol B (6), together with two phenolic compounds, p-hydroxybenzaldehyde and (7) 2,3,5-trihydroxybenzoic acid (8) were effectively isolated. The isolation of these compounds was the first report from this species.