Evaluating generative AI models for explainable pathological feature extraction in lung adenocarcinoma: grading assessment and prognostic model construction
GenAI models demonstrated significant potential in lung adenocarcinoma pathology, with Claude-3.5-Sonnet exhibiting superior performance in grading prediction and robust prognostic capabilities. These findings indicate promising applications of AI in lung adenocarcinoma diagnosis and clinical management.
Authors
- Bufu Tang (ORCID: https://orcid.org/0000-0003-3525-4433)
- Wenyi Gan (ORCID: https://orcid.org/0000-0003-1886-8062)
- Quan Cheng (ORCID: https://orcid.org/0000-0003-2401-5349)
- Dongqiang Zeng (ORCID: https://orcid.org/0000-0002-1573-5371)
- Zhenfa Zhang (ORCID: https://orcid.org/0000-0002-9627-2590)
- Lingxuan Zhu (ORCID: https://orcid.org/0009-0001-9077-408X)
- Suyin Feng
- Hank Z. H. Wong
- Yuying Feng (ORCID: https://orcid.org/0000-0002-0581-2476)
- Peng Luo (ORCID: https://orcid.org/0000-0002-8215-2045)
- Mingjia Xiao
- Weiming Mou (ORCID: https://orcid.org/0009-0007-1089-6516)
- Guangdi Chu (ORCID: https://orcid.org/0000-0002-2963-1741)
- Aimin Jiang (ORCID: https://orcid.org/0000-0002-4092-342X)
- Junyi Shen (ORCID: https://orcid.org/0009-0005-7426-6527)
- Chunrong Dong
- Anqi Lin (ORCID: https://orcid.org/0000-0002-6324-0410)
- Shengkun Peng (ORCID: https://orcid.org/0000-0001-5624-2816)
- Z. P. Xie (ORCID: https://orcid.org/0009-0008-7394-5183)
- Jian Zhang (ORCID: https://orcid.org/0000-0001-7217-0111)
- Qi Chang (ORCID: https://orcid.org/0000-0001-6200-1111)
- Zaoqu Liu (ORCID: https://orcid.org/0000-0002-0452-742X)
- Yifeng Bai (ORCID: https://orcid.org/0000-0002-5595-3963)
Institutions
- Qingdao University (CN)
- Jiangnan University (CN)
- Central South University (CN)
- University of Electronic Science and Technology of China (CN)
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Chinese University of Hong Kong (HK)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fudan University (CN)
- Wenzhou Medical University (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Quzhou City People's Hospital (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Nanfang Hospital (CN)
- Zhuhai People's Hospital (CN)
- Wuxi Fourth People's Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- Zhujiang Hospital (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- County Hospital (GB)
- Shanghai First People's Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Kangda College of Nanjing Medical University
- Southern Medical University (CN)
- Nanjing Medical University (CN)
- University of Hong Kong (HK)
- South China University of Technology (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1097/js9.0000000000002507
- Citations
- 6
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 8.16