Epidermal Growth Factor Receptor Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review

Liquid and tissue NGS should be used in combination to guide treatment and monitor treatment response. Osimertinib may be particularly effective in metastatic NSCLC with EGFR-KDD mutations.

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Publication Details

Journal
Case Reports in Oncology
Published
2025-05-28
DOI
https://doi.org/10.1159/000545543
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Epidermal Growth Factor Receptor Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review

Matthew M. Mirsky, Ankit Mangla, Jenny Gong
Case Reports in Oncology
Lung Cancer Treatments and Mutations
article

Epidermal Growth Factor Receptor Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review

Matthew M. Mirsky, Ankit Mangla, Jenny Gong
article en

Abstract

Liquid and tissue NGS should be used in combination to guide treatment and monitor treatment response. Osimertinib may be particularly effective in metastatic NSCLC with EGFR-KDD mutations.

Case Reports in OncologyVol. 18(1)
University Hospitals of Cleveland (US)
Openalex Percentile: Top 80%
Lung Cancer Treatments and Mutations
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Epidermal Growth Factor Receptor Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review — Matthew M. Mirsky, Ankit Mangla, et al. · Case Reports in Oncology (2025) | TGRS Research Map | TGRS