Investigation of the quality of life of cervical cancer patients and analysis of clinical data based on the CC-PRO137 scale.

e17523 Background: Cervical cancer is the most prevalent malignant neoplasm of the female reproductive system. China accounts for close to 1/5 of the world's incidence cases. The physical, psychological, and social life issues that accompany cervical cancer treatment are what physicians need to focus on. Methods: This study prospectively recruited patients who underwent surgical for cervical cancer at 7 regional medical centers in China between July 2021 and December 2023. Subjects were followed up on the CC-PRO137 (Cervical Cancer Patient Reported Clinical Outcome Assessment Scale) scale at two time points: within 6 months after the end of treatment and after 12 months period. Physical and psychological functioning and social life status of the patients were investigated. Subjects' recovery status was compared across conditions, and differences in their quality of life were analyzed and compared using multiple linear regression equations. Results: A total of 368 subjects were followed up for 2 time periods. In physiological field, the patient's urinary function is most affected in the short term. Relative to open surgery, patients undergoing laparoscopic surgery were more severely impaired in urinary function (URI: t=-2.985, p=0.023), lymphedema status (LYM: t=-2.465, p=0.014) and neurological function (NEU: t=-2.996, p=0.003). Laparoscopic surgery increases patients' social support burden (SUP: t=-2.016, p=0.044). In psychological field, radiotherapy exacerbated symptoms of anxiety and depression, as well as feelings of shame associated with the disease (ANX: t=-2.256, p=0.025; DEP: t=-2.295, p=0.022; SHA: t=-2.674, p=0.008). Social lives are only affected by the patient's age (LIF: t=-4.677, p=0.000). After 12 months, the impact of radiotherapy on bowel function (BOW: t=-2.044, p=0.042) and sexual life (SEX: t=-2.705, p=0.007) was found to be enduring. Conclusions: Clinicians should grasp the feedback of patients' recovery outside the hospital, so as to be able to give more immediate and targeted help to patients. Furthermore, for patients, cognisance of potential outcomes can facilitate more effective management of expectations.