A case of diagnosis and treatment of mediastinal Langerhans cytosis

Langerhans cytosis is characterized by mediastinal and thymus occupation and is relatively rare in clinical practice. For patients who tolerate surgery for a single or local lesion, surgical removal of the primary lesion should be considered. However, for patients with multiple lesions or distant metastases, clinicians should evaluate whether surgery will benefit the patient. After surgical treatment, targeted therapy or immunotherapy should be performed.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2025-05-28
DOI
https://doi.org/10.1186/s13019-025-03489-5
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

A case of diagnosis and treatment of mediastinal Langerhans cytosis

Yourong Chen, Yifei Lu, Daying Liang, Yumeng Niu et al.
1 links
Journal of Cardiothoracic Surgery
Histiocytic Disorders and Treatments
article

A case of diagnosis and treatment of mediastinal Langerhans cytosis

Yourong Chen, Yifei Lu, Daying Liang, Yumeng Niu, Yifan Wang, Lei Xian
article en

Abstract

Langerhans cytosis is characterized by mediastinal and thymus occupation and is relatively rare in clinical practice. For patients who tolerate surgery for a single or local lesion, surgical removal of the primary lesion should be considered. However, for patients with multiple lesions or distant metastases, clinicians should evaluate whether surgery will benefit the patient. After surgical treatment, targeted therapy or immunotherapy should be performed.

Journal of Cardiothoracic SurgeryVol. 20(1)
Guangxi Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 84%
Histiocytic Disorders and Treatments
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