Feeding infant formula with low sn-2 palmitate causes changes in newborn’s intestinal environments through an increase in fecal soaped palmitic acid
Our clinical data showed significant associations between higher fecal soaped PA levels and lower Bifidobacteria occupancy in the newborn gut, which agreed well with the report of the in vitro study. Our study also suggests that feeding infant formula with low sn-2 palmitate causes changes in the intestinal environment through an increase in fecal soaped palmitic acids.
Authors
- Satsuki Kakiuchi (ORCID: https://orcid.org/0009-0003-7646-7643)
- Hiroko Arai (ORCID: https://orcid.org/0009-0008-0781-0731)
- Keigo Sato (ORCID: https://orcid.org/0000-0002-1209-1179)
- Shinji Jinno (ORCID: https://orcid.org/0000-0002-1971-4631)
- Hiromichi Shoji (ORCID: https://orcid.org/0000-0003-2532-8910)
- Hitoshi Yoda (ORCID: https://orcid.org/0009-0005-6465-9327)
- Naoto Takahashi (ORCID: https://orcid.org/0000-0003-3749-5871)
- Kenichi Masumoto
- Toshiaki Shimizu
- Atsushi Ito (ORCID: https://orcid.org/0009-0000-6344-1581)
Institutions
- Toho University (JP)
- Juntendo University (JP)
- University of Tokyo Hospital (JP)
- Oji Holdings (Japan) (JP)
- Japan Food Research Laboratories (JP)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-28
- DOI
- https://doi.org/10.1371/journal.pone.0324256
- Citations
- 3
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.36
Funders
- Food Science Institute Foundation