Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania

1. Strengthen mobile diagnostic services by increasing their frequency and coverage, enabling timely diagnosis and treatment. 2. Enhance the TB symptom screening tool by including a symptom-independent test, such as a chest X-ray, as the symptoms of illicit drug use can mask and mimic TB symptoms making diagnosis challenging. 3. Address stigma and misconceptions through peer-led education and awareness campaigns that utilize audio-visual materials tailored to PWUD. This will promote adherence to IPC measures and create a more supportive environment for TB ACF activities. 4. Use anti-TB with minimal interactions with opiates or shorter TB treatment regimens to prevent withdrawal symptoms and improve adherence.

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Publication Details

Journal
PLoS ONE
Published
2025-05-28
DOI
https://doi.org/10.1371/journal.pone.0310069
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania

Samuel Likindikoki, Jennifer M. Belus, Linda Minja, Doreen Pamba et al.
PLoS ONE
Tuberculosis Research and Epidemiology
article

Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania

Samuel Likindikoki, Jennifer M. Belus, Linda Minja, Doreen Pamba, Jerry Hella, Cassian Nyandindi, Klaus Reither, Lilian Tina Minja, Jessie Mbwambo, Kilian Mlalama
article en

Abstract

1. Strengthen mobile diagnostic services by increasing their frequency and coverage, enabling timely diagnosis and treatment. 2. Enhance the TB symptom screening tool by including a symptom-independent test, such as a chest X-ray, as the symptoms of illicit drug use can mask and mimic TB symptoms making diagnosis challenging. 3. Address stigma and misconceptions through peer-led education and awareness campaigns that utilize audio-visual materials tailored to PWUD. This will promote adherence to IPC measures and create a more supportive environment for TB ACF activities. 4. Use anti-TB with minimal interactions with opiates or shorter TB treatment regimens to prevent withdrawal symptoms and improve adherence.

PLoS ONEVol. 20(5)
Ifakara Health Institute (TZ), Drug Enforcement Administration (US), Muhimbili University of Health and Allied Sciences (TZ), Swiss Tropical and Public Health Institute (CH), University of Basel (CH), University Hospital of Basel (CH), Muhimbili National Hospital (TZ), National Institute for Medical Research (TZ)
National Institute for Medical Research
Good health and well-being
Openalex Percentile: Top 85%
Tuberculosis Research and Epidemiology
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