gtexr: A convenient R interface to the Genotype-Tissue Expression (GTEx) Portal API
The Genotype-Tissue Expression (GTEx) project (GTEx Consortium, 2013, 2020) is a comprehensive public resource for studying tissue-specific gene expression and regulation in human tissues.Through systematic analysis of RNA sequencing data from 54 non-diseased tissue sites across nearly 1000 individuals, GTEx provides crucial insights into the relationship between genetic variation and gene expression.This data is accessible through the GTEx Portal API (GTEx Consortium, 2023), enabling programmatic access to human gene expression data.
Authors
- Abraham Olvera‐Barrios (ORCID: https://orcid.org/0000-0002-3305-4465)
- Benjamin Zuckerman (ORCID: https://orcid.org/0000-0002-0077-6074)
- Chuin Ying Ung (ORCID: https://orcid.org/0000-0001-8487-4589)
- Robert Luben (ORCID: https://orcid.org/0000-0002-5088-6343)
- Alasdair Warwick (ORCID: https://orcid.org/0000-0002-0800-2890)
Institutions
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Moorfields Eye Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- The Journal of Open Source Software
- Published
- 2025-05-28
- DOI
- https://doi.org/10.21105/joss.08249
- Citations
- 1
- Primary Topic
- Gene expression and cancer classification
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Wellcome Trust
- Cancer Research UK
- National Institute for Health and Care Research
- Department of Health and Social Care
- Moorfields Eye Hospital NHS Foundation Trust
- National Institutes of Health
- Medical Research Council
- National Heart, Lung, and Blood Institute
- National Institute of Mental Health
- National Institute on Drug Abuse
- National Human Genome Research Institute
- NIH Office of the Director
- National Cancer Institute
- National Institute of Neurological Disorders and Stroke
- Common Fund