Development of a prognostic model for overall survival in neuroblastoma based on Schwann cell-specific genes, clinical predictors, and MYCN amplification

This study developed a model for predicting OS in NBL by integrating Schwann cell-specific genes, clinical factors, and the TME. The model highlights the importance of specific cellular contributions to prognosis and provides a more personalized approach to NBL treatment, particularly for high-risk patients.

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Publication Details

Journal
Translational Cancer Research
Published
2025-05-01
DOI
https://doi.org/10.21037/tcr-24-2048
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of a prognostic model for overall survival in neuroblastoma based on Schwann cell-specific genes, clinical predictors, and MYCN amplification

Yingru Wu, Ziru Li, Jing Liu
Translational Cancer Research
Neuroblastoma Research and Treatments
article

Development of a prognostic model for overall survival in neuroblastoma based on Schwann cell-specific genes, clinical predictors, and MYCN amplification

Yingru Wu, Ziru Li, Jing Liu
article en

Abstract

This study developed a model for predicting OS in NBL by integrating Schwann cell-specific genes, clinical factors, and the TME. The model highlights the importance of specific cellular contributions to prognosis and provides a more personalized approach to NBL treatment, particularly for high-risk patients.

Translational Cancer ResearchVol. 14(5)
Capital Institute of Pediatrics (CN), Children's Hospital of Capital Institute of Pediatrics (CN)
Openalex Percentile: Top 81%
Neuroblastoma Research and Treatments
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