To Study Prevalence of Ocular Surface Diseases in Human Immunodeficiency Virus Positive Patients and its Correlation with CD4 Count – a Cross Sectional Observational Study

To determine prevalence of ocular surface diseases in Human Immunodeficiency Virus positive patients and its correlation with CD4 count a cross sectional observational study. A cross sectional observational study. The present observational study was conducted at a tertiary health care institute in Central India. There was a total of 233 Human Immunodeficiency Virus positive patients who were enrolled in this study and their prevalence was calculated for Ocular Surface Diseases which was also compared with their CD4+ cell count. Permission to conduct the study on Human Immunodeficiency Virus positive patients was taken from Maharashtra State Acquired Immunodeficiency Disease Control Society and National Acquired immunodeficiency disease Control Organisation. Statistical analysis done using MSExcel2019 and Graph pad prism. The overall prevalence of OSD was 36.5% and that most common OSD found were DED, Blepharitis, and Conjunctivitis. Most of study participants with ocular surface diseases had CD4 cell count which was statistically significant. The present study determines the prevalence of ocular manifestations in the enrolled study participants who are Human Immunodeficiency Virus positive, where CD4 cell counts were found to be between low and very low for most of the study participants. Keywords: Human immunodeficiency virus positive participants, ocular surface diseases, CD4 cell count, dry eye disease.