Limbal stem cell deficiency: a dreaded complication of chickenpox in children

We report a rare case of Limbal Stem Cell Deficiency (LSCD) in a 10-year-old child following chickenpox. The child presented with persistent ocular symptoms, including pain, redness, and photophobia, two months after the resolution of systemic chickenpox. Ophthalmic examination revealed conjunctival hyperemia, 360° conjunctivalization, corneal neovascularization, and an epithelial defect. LSCD, characterized by corneal neovascularization and conjunctivalization, can occur after viral infections, including herpes zoster. To our knowledge, this is the first reported case of LSCD following chickenpox in a child. Early recognition and collaborative care between pediatricians and ophthalmologists are essential for effective management.

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Publication Details

Journal
Oxford Medical Case Reports
Published
2025-05-01
DOI
https://doi.org/10.1093/omcr/omaf037
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Limbal stem cell deficiency: a dreaded complication of chickenpox in children

Houda Bezza, F. Elasri, M. Kriet, Houssaine Ait Lhaj et al.
1 links
Oxford Medical Case Reports
Corneal Surgery and Treatments
article

Limbal stem cell deficiency: a dreaded complication of chickenpox in children

Houda Bezza, F. Elasri, M. Kriet, Houssaine Ait Lhaj, Oumayma Elmansouri, Assia Lemkhoudem
article en

Abstract

We report a rare case of Limbal Stem Cell Deficiency (LSCD) in a 10-year-old child following chickenpox. The child presented with persistent ocular symptoms, including pain, redness, and photophobia, two months after the resolution of systemic chickenpox. Ophthalmic examination revealed conjunctival hyperemia, 360° conjunctivalization, corneal neovascularization, and an epithelial defect. LSCD, characterized by corneal neovascularization and conjunctivalization, can occur after viral infections, including herpes zoster. To our knowledge, this is the first reported case of LSCD following chickenpox in a child. Early recognition and collaborative care between pediatricians and ophthalmologists are essential for effective management.

Oxford Medical Case ReportsVol. 2025(5)
Hôpital Militaire Avicenne (MA)
Good health and well-being
Openalex Percentile: Top 82%
Corneal Surgery and Treatments
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