A fatal case of cytomegalovirus pneumonia with coexisting <i>aspergillus</i> infection in a immunodeficient patient

<b>Introduction</b>: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. <b>Patient concerns</b>: The patient was an older woman with low immune function but was not a transplant patient. <b>Diagnosis</b>: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. <b>Interventions</b>: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. <b>Outcome</b>: The patient's condition deteriorated and she eventually died of myocardial infarction. <b>Conclusion</b>: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.

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Publication Details

Journal
Oxford Medical Case Reports
Published
2025-05-01
DOI
https://doi.org/10.1093/omcr/omaf060
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

A fatal case of cytomegalovirus pneumonia with coexisting aspergillus infection in a immunodeficient patient

Shaosen Chen, Kun-Lun Huang
Oxford Medical Case Reports
Cytomegalovirus and herpesvirus research
article

A fatal case of cytomegalovirus pneumonia with coexisting aspergillus infection in a immunodeficient patient

Shaosen Chen, Kun-Lun Huang
article en

Abstract

<b>Introduction</b>: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. <b>Patient concerns</b>: The patient was an older woman with low immune function but was not a transplant patient. <b>Diagnosis</b>: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. <b>Interventions</b>: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. <b>Outcome</b>: The patient's condition deteriorated and she eventually died of myocardial infarction. <b>Conclusion</b>: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.

Oxford Medical Case ReportsVol. 2025(5)
Foshan Second People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 83%
Cytomegalovirus and herpesvirus research
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